Flucort-H Fluocinolone Acetonide Cream 0.1% 30g
Flucort-H Fluocinolone Acetonide 0.1% lotion is a strong topical corticosteroid cream for the skin. It effectively reduces the actions of substances in the body that cause itching and redness, dryness, crusting, scaling, inflammation, and discomfort of various skin conditions. Flucort-H Fluocinolone Acetonide is used to for entire treatment several skin conditions such as allergies, skin inflammation, eczema, seborrhea, and psoriasis. Flucort-H can be used with moisturisers for treating inflammatory skin conditions that are common like eczema & dermatitis.
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Flucort-H Fluocinolone Acetonide Cream Usage and Benefits
- Use the fluocinolone acetonide cream on the skin only, don’t utilize it on underarms, groin, or the facial skin unless you have been directed to do so by your physician.
- Wash and dry your hands. Clean and dry the affected region.
- Do not bandage, cover, or wrap the area unless directed to do this by your physician.
- Wash your hands after applying the flucinolone acetonide cream.
- When implementing this medication close to the eyes, avoid getting it because this could worsen or cause glaucoma. Additionally, avoid getting this drug in the nose or mouth.
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Side Effects and Precautions while using Flucort -H
In case you have some allergies to fluocinolone or to other corticosteroids (hydrocortisone, prednisone) tell your healthcare provider. Before applying this medicated cream, tell your health care provider your medical history, especially of: diabetes, poor blood circulation, immune system issues. If there’s an illness or sore in the area to be medicated, don’t use. Though very unlikely, it is possible this medication will probably be absorbed into your bloodstream. This might have undesirable consequences that may require additional corticosteroid treatment. During pregnancy, this medication needs to be utilized only when clearly needed. Talk about the risks and benefits together with your doctor. It is not known whether this drug passes into breast milk when applied to your skin. Consult with your healthcare earlier.
Mechanism of Work of Flucinolone Acetonide cream :
Fluocinolone Acetonide is a corticosteroid which corresponds to the cytosolic glucocorticoid receptor. Following binding the receptor the newly formed receptor-ligand complicated translocates itself to the cell nucleus, where it results in many glucocorticoid response elements (GRE) in the promoter region of the target genes. The DNA bound receptor subsequently interacts with all essential transcription factors, inducing the growth in expression of specific target genes. The anti-inflammatory action of corticosteroids are believed to include lipocortins, phospholipase A2 inhibitory proteins that, through inhibition arachidonic acid, restrain the biosynthesis of prostaglandins and leukotrienes. Especially glucocorticoids cause lipocortin-1 (annexin-1) synthesis, which then binds to cell membranes preventing the phospholipase A2 from coming in contact with its substrate arachidonic acid. This leads to diminished eicosanoid production. Cyclooxygenase (both COX-1 and COX-2) expression can be suppressed, potentiating the result. In another words, the two major products in inflammation Prostaglandins and Leukotrienes are inhibited by the action of Glucocorticoids.